REALS NIGHT AID
Everyone benefits from a good night’s sleep. If you have followed the usual tips for getting enough sleep, sleeping on a regular schedule, avoiding caffeine and daytime naps, exercising regularly, and managing stress and still, it’s been weeks and a good night’s sleep remains elusive, then it is time to use Reals Night Aid.
Description
Everyone benefits from a good night’s sleep. If you have followed the usual tips for getting enough sleep, sleeping on a regular schedule, avoiding caffeine and daytime naps, exercising regularly, and managing stress and still, it’s been weeks and a good night’s sleep remains elusive, then it is time to use Reals Night Aid.
Reals Night Aid is our brand of an over the counter sleep aid. It contains diphenhydramine hydrochloride 50mg which is a sedating antihistamine. It works by reducing the time needed to fall asleep and increases the depth and quality of sleep. Reals Night Aid is used to aid relief of temporary sleep disturbance (difficulties sleeping) in adults and children over 16 years of age.
The Indication area also includes:
Reals Night Aid also takes care of
- Sneezing
- Runny Nose
- Watery Eyes
- Hives
- Skin Rash
- Itching
- Cold and Allergy Symptoms
Clinical Pharmacology
Antihistamine action: Antihistamines compete for H-receptor sites on the smooth muscle of the bronchi, GI tract, uterus and large blood vessel; by binding to cellular receptors, they prevent access of histamine and suppress histamine-induced allergic symptoms, even though they don’t prevent its release.
Antivertigo, antiemetic and antidyskinetic actions: Central antimuscarinic actions of antihistamines probably are responsible for these effects of diphenhydramine.
Antitussive action: Drug suppresses the cough reflex by a direct effect on the cough center.
Sedative action: Mechanism of the CNS depressant effects of diphenhydramine is unknown.
Anesthetic action: Drug is structurally related to local anesthetics, which prevent initiation and transmission of nerve impulses, this the probable source of its tropical and local anesthetic effects.
Products Profile
NAFDAC No
B4-6357
Other Info
Absorption: Well absorbed from GI tract.
Distribution: Distributed widely throughout the body, including the CNS; drug crosses the placental barrier and appears in breast milk. The drug is about 82% protein-bound.
Metabolism: About 50% to 60% of an oral dose of diphenhydramine is metabolized by the liver before reaching the systemic circulation (first-pass effect); virtually all available drug is metabolized by the liver within 24 to 48 hours.
Excretion: Plasma elimination half-life of the drug is about 21/2 to 9 hours; drug and metabolites are excreted primarily in the urine.
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